Applications Data Analyst Lead

Sequencing technology fueled advances in applications such as SNP identification and molecular quantitation at a massive rate and scale, but a significant amount of critical genetic information remains inaccessible.

10X Genomics is looking for an outstanding scientist to join its Applications Development group. The scientist must have a passion for innovating new applications that use Next Generation Sequencing technologies to drive discovery and improve human health. The scientist must be able to learn quickly, creatively solve problems, and have a deep understand of NGS technologies. Additionally, the candidate must have strong data analysis skills. The ideal candidate will have a PhD and postdoctoral experience in either population genomics, cancer genomics or clinical genomics.

* Develop and manage collaborations with external scientists to enable them to demonstrate the power of the 10X Genomics platform. * Work with key scientists to develop new applications that take advantage of 10X technology. * Analyze data for a variety of applications, including variant identification, assembly assessment and metagenomics applications. * Work with key collaborators to present data at scientific conferences as well publish results in scientific journals. * Develop scientific materials to be used in webinars or other platforms to highlight the advantages of the 10X genomic platform. * Work with core product development teams to improve products and enable novel applications as driven by the scientific community.

**Required Skills and Background** * PhD or equivalent in genomics, cancer genomics or clinical genomics. * Experience analyzing large sequencing data sets using Python or R * Solid knowledge of commonly used tools (BWA, GATK, FreeBayes, etc) * Familiarity with the command line and source control. * Deep understanding of the NGS applications space, particularly as related to human health (e.g., sequencing applied to RNA, cancer, immune repertoire, single cells) * Experience with existing NGS platforms (e.g., Illumina, Ion Torrent, PacBio, etc.) * Demonstrated ability to trouble-shoot complex problems and to work effectively in a multi-disciplinary team * An eagerness to dramatically improve NGS tools * Strong organizational skills * Strong written and oral communication skills demonstrated with peer-reviewed publications and conference presentations * Demonstrated ability to maintain relationships with customers or external collaborators **Desired Skills and Background** * Understanding of statistical methods used in RNA sequencing experiments * Experience with NGS-related products such as Agilent SureSelect target capture, Ion AmpliSeq, Fluidigm single cell sequencing, etc. * Experience with DNA and/or RNA extraction methods * Deep knowledge of RNA or cellular biology in cancer or immunology contexts * Experience with other laboratory assays including real-time PCR, droplet digital PCR * Understanding of gene editing methods including CRISPR