Senior Development Scientist
Yoh
(King of Prussia, Pennsylvania)Yoh covers the diverse talent and workforce management needs in the Aviation, Engineering, Health Care, IT, Life Sciences, Media & Entertainment and Telecom industries. You can be confident that we have the right talent and managed solution for you. You need it. Yoh has it!
- Develop and implement various methods for characterizing protein therapeutics aggregates and particles matters formation
- Design and execute forced degradation studies including protocol drafting, sample preparations, coordinate sample testing, perform assigned testing and aid in data analysis and interpretation
- Develop methods for characterizing and quantifying various protein therapeutics higher order structure properties such as secondary and tertiary structure
What You Need to Bring to the Table:
- Masters degree with 2-5 years experience in biotech or pharmaceutical industry
- Extensive knowledge and experience in protein structure analysis such as secondary and tertiary structure, protein folding-unfolding, aggregates, and particles characterization and quantification using various spectroscopic and biophysical techniques including FTIR, CD, DSC, AUC, Fluorescence, SEC-MALS, particle analysis technologies (FlowCam, MFI, and HIAC)
- Experience in employing protein higher order structure characterization in the development of protein therapeutics including process development, product characterization, degradation pathway analysis and comparability evaluation
- Experienced in designing and executing forced degradation studies of protein therapeutics and developing strategies in establishing/understand protein structure -function relationships
The Big Picture - Top Skills You Should Possess:
- Protein structure analysis
- Protein degradation
Benefits | Benefits included |
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Questions
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- Data Analysis
- Design
- Process Development
- Testing
- Biotechnology
- Developing Strategies
- Pharmaceutical
- Protein Chemistry
- Fourier Transform Infrared Spectroscopy (FTIR)
- Area under the curve
- dye-sensitized solar cell
- Fluorescence
- SEC-MALS
- FlowCam
- Melt flow index
- Hepatic Intra-Arterial Catheters
- Protein degradation
- Protein structure analysis

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