Principal Scientist for Modeling and Data Sciences

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us.

Under the direction of a DPEM Executive Director, the Principal Scientist provides strategic development and use of industry-leading predictive and economic models to enhance our understanding of disease and to quantify and communicate the value of our products to patients, providers, and payers. The scientist provides model-based business insights across all phases of drug and vaccine development. In addition, she/he serves as the DPEM lead for one or more value evidence teams to develop health economic, disease, and predictive models to enable business insights for the product.

* Utilize discovery, real world evidence, clinical trial and published data, and publicly available information and tools to provide economic and integrated models to answer key questions in all phases of drug and vaccine development – Phase I through loss of data exclusivity. * Advance the use of integrated quantitative approaches, focusing on economic, disease, and predictive modeling and simulation in partnership with other internal groups and external organizations. * Liaise with statistics, pharmacokinetics, pharmacodynamics teams, IT, data management, and other quantitative groups in Merck to optimize strategy and align resources for their respective products. * Maintain awareness of external data, models and IT environment to collaborate across relevant internal stakeholders to enhance Merck capabilities in modeling, simulation, and data visualization. * Work closely with external (other companies, payers, academic and regulatory) collaborators and partners to assure that new methodologies, models and advanced analytics are fully utilized for our products. * Partner in defining and implementing the DPEM vision and strategy to develop an innovative, world class Center of Excellence in data science as well as predictive and economic modeling. * Ensure sharing of work product and relevant best practices across the Merck enterprise.

**Education:** PhD (preferred) or Masters in Quantitative Sciences such as Health Economics, Mathematics, Predictive Modeling, Statistics, Operations Research, Physics, Engineering or closely related field with 5 or more years beyond PhD or 7 or more years beyond Masters of relevant experience in healthcare **Required:** * Exceptional leadership skills with experience in leading teams * Experience in the design and development of model approaches to enable internal and external decisions * Experience in managing resources and driving implementation * Exceptional technical and problem solving skills * Deep knowledge and experience in the application of predictive modeling to solve problems in the pharmaceutical or biotechnology industry to enable internal and external decisions * Experience in presenting to Reimbursement, Regulatory or Health Agencies * Strong record of scientific presentations and research publications in peer-reviewed journals * Excellent communication skills (oral and written) are expected **Preferred:** Health and economic modeling of vaccination programs