Scientist/Engineer

Bristol-Myers Squibb is a global BioPharma company firmly focused on its mission to discover, develop and deliver innovative medicines to patients with serious diseases.

The Scientist/Engineer will report to an Upstream Sr. Scientist/Engineer, and will collaborate with a group of Ph.D. scientists and associate scientists to develop robust and scalable mammalian cell culture processes for late stage biologics in BMS’s very robust and very exciting pipeline. The candidate will work closely with the downstream team, analytical team and other matrix organizations to drive speed to clinical and work with manufacturing sites within the BMS network or Third Party Manufacturing to deliver robust, scalable and economical processes for late stage clinical and commercial supply.

* Hands-on operation of lab scale bioreactors for mammalian cell culture processes. * Upstream process design, optimization, and tech transfer. * Support process scale up activities in pilot plant and clinical manufacturing sites. * Prepare/review technical documents including development /tech transfer reports, batch records, SOPs and CMC regulatory submissions. * Participate on cross functional teams to progress both early and late stage drug candidates. * Train junior team members in lab operations. * Recommend innovative new technologies and perform the necessary experiments for evaluation and implementation.

* M.S. or Ph.D.: Chemical/Biochemical Engineering, Biochemistry, Biophysics, Cell Biology or equivalent with a minimum of 4+ years of industry and/or academic experience preferred. * In depth understanding and hands on experience in upstream process development, bioreactor operation and scale-up/down, media development. * Practical experience with downstream processing and analytical techniques relating to glycoprotein attributes. * Knowledge of statistical experimental design and data analysis. * Knowledge of cGMPs as applied to process development and scale up. * Excellent oral and written communication skills. * Ability to work collaboratively in a team environment.