Principal Engineer

Amgen is one of the world’s leading biotechnology companies. Amgen is a values-based company, deeply rooted in science and innovation to transform new ideas and discoveries into medicines for patients with serious illnesses.

The Principal Engineer - working in Amgen's Discovery Technologies organization - will be primarily responsible for the successful implementation of microtiter-plate based experiments in a state-of-the-art uHTS laboratory. - Duties include programming, calibrating, and troubleshooting diverse HTS equipment: robotic arms, liquid dispensers and plate-reading instruments. - The candidate will also work closely in a team environment with biologists, biochemists, information technology/software development staff and engineering support personnel to successfully develop, transfer and execute assays on the uHTS platform and ancillary equipment. - Quantitative analysis and quality control of HTS data will also be significant responsibilities. The incumbent will also train and assist engineers and scientists to use ancillary HTS equipment.

Basic Qualifications - Doctorate degree & 2 years of Engineering experience OR Master's degree & 6 years of Engineering experience OR Bachelor's degree or & 8 years of Engineering experience OR Associate's degree & 10 years of Engineering experience OR High school diploma / GED & 12 years of Engineering experience Preferred Qualifications - B.S. or M.S. in physical sciences; B.S.E. or M.S.E. in chemical-, mechanical-, electrical-, biomedical- or bio- engineering; - 5+ years of experience in 384 & 1536-well microtiter plate HTS methodology and HTS assay development as well as experience in HTS spectroscopy and/or imaging techniques; - experience operating and maintaining HTS robotics (especially Staubli/Stäubli based systems), automated liquid handlers and plate reader instrumentation (for example, Perkin Elmer Envision, Molecular Devices FLIPR, Perkin Elmer Opera/Operetta); - experience with Microsoft Office, Access, Sharepoint & Project software; - experience with Genedata, Mosaic and Spotfire software; SQL, PL/SQL, Pipeline Pilot, and automation software programming skills (for example VAL, PLC-IEC61131, C++ and /or C#); - demonstrated ability to work in a team environment; - excellent communication skills; - demonstrated ability to report relevant results of their work to project teams and management; - demonstrated successful interpersonal relationships with peers and colleagues in other scientific disciplines; and - demonstrated success in performing novel HTS-related research and mentoring junior technical staff.